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Career Opportunities with Summit Therapeutics Sub, Inc.

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Ivonescimab, known as SMT112, is a novel, potential first-in-class investigational bispecific antibody combining immunotherapy via PD-1 blockade with anti-angiogenesis effects by blocking VEGF. Ivonescimab exhibits unique cooperative binding to its targets with higher affinity when both PD-1 and VEGF are present.

Summit has initiated clinical development of ivonescimab in non-small cell lung cancer (NSCLC), with three active Phase III trials:

1. HARMONi: A Phase III trial evaluating ivonescimab with chemotherapy versus placebo with chemotherapy in EGFR-mutated, locally advanced or metastatic non-squamous NSCLC patients who progressed after third-generation EGFR TKI treatment.
2. HARMONi-3: A Phase III trial assessing ivonescimab with chemotherapy versus pembrolizumab with chemotherapy in first-line metastatic NSCLC.
3. HARMONi-7: A Phase III trial comparing ivonescimab monotherapy to pembrolizumab monotherapy in first-line metastatic NSCLC with high PD-L1 expression.

Ivonescimab is an investigational therapy not yet approved in the US or Europe but was approved in China in May 2024. It has received Fast Track designation from the FDA for the HARMONi trials.

Overview of Role:

The Associate Director of Facilities Management will oversee operations at our U.S. and European offices, ensuring security, compliance, cost-efficiency, and an optimal employee environment. Responsibilities include vendor management, regulatory compliance, physical security, and strategic planning to support business growth. This role requires a proactive leader capable of managing daily operations and shaping long-term facilities strategies globally.

Responsibilities:

• Lead daily operations ensuring efficient space utilization.
• Implement security, safety, and emergency protocols.
• Ensure compliance with building codes, healthcare regulations, and environmental standards.
• Manage vendor relationships and service contracts.
• Enhance employee experience through facilities services.
• Implement IT solutions for facility management and efficiency.
• Perform other duties as assigned.

Qualifications:

• Bachelor's degree in Facilities Management, Engineering, Business, or related field.
• At least 7 years of facilities management experience, including multi-office/global oversight.
• Expertise in security, vendor management, and compliance standards (OSHA, ADA, HSE).
• Proven ability to manage budgets, negotiate contracts, and lead initiatives.
• Strong leadership, communication, and stakeholder influence skills.
• Certified Healthcare Facility Manager (CHFM) preferred.
• Experience with IT-enabled facilities solutions (automation, space booking, asset tracking).

The salary range for this role is $168,000-$180,000 annually, with actual compensation based on experience, skills, certifications, and location. Benefits may include bonuses, stock options, and other variables.

Summit does not accept referrals from employment agencies without prior approval. Agencies must contact our Talent Acquisition team at ...@smmttx.com for authorization.